Proper Name: Cholecalciferol

Common Name: Vitamin D

Evidence of Efficacy: statement to the effect of
Vitamin D deficiency or imbalance plays a role in the symptoms of mood disorders. Observational and experimental studies have shown an association between vitamin D and anxiety^1, depression^2,3 and premenstrual syndrome^4,5.

References:

1. Arlt W, Fremerey C, Callies F, Reincke M, Schneider P, Timmermann W, Allolio B.; Well-being, mood and calcium homeostasis in patients with hypoparathyroidism receiving standard treatment with calcium and vitamin D. Eur J Endocrinol. Feb;146(2):215-22, 2002.
2. Arasteh K. A beneficial effect of calcium intake on mood. J Orthomol Psychiatry 9(4):199-204, 1994.
3. Deluca HF.; The vitamin D system: a view from basic science to the clinic. Clin Biochem. Oct;14(5):213-22, 1981.
4. Thys-Jacobs S. Vitamin D and calcium in menstrual migraines. Headache 34(9):544-6, 1994.
5. Thys-Jacobs S.; Micronutrients and the premenstrual syndrome: the case for calcium. J Am Coll Nutr. Apr;19(2):220-7, 2000.