Proper Name: Molybdenum

Common Name: Molybdenum

Evidence of Efficacy: statement to the effect of Molybdenum deficiency or imbalance plays a role in the symptoms of mood disorders. Observational and experimental studies have shown an association between molybdenum and bipolar disorder¹. There is also strong evidence for the neuro-protective role of molybdenum^2,3,4.

References:

1. Naylor GJ, Smith AH, Bryce-Smith D, Ward NI. Trace elements in manic depressive psychosis. J Affect Disord. 1985 Mar-Apr; 8(2): 131-6.
2. Woo WH, Yang H, Wong KP, Halliwell B. Sulphite oxidase gene expression in human brain and in other human and rat tissues. Biochem Biophys Res Commun. 2003 Jun 6; 305(3): 619-23.
3. Johnson JL, Rajagopalan KV. The oxidation of sulphite in animals systems. Ciba Found Symp. 1979; (72): 119-33.
4. Yamamoto T, Moriwaki Y, Takahashi S, Tsutsumi Z, Tuneyoshi K, Matsui K, Cheng J, Hada T. Identification of a new point mutation in the human molybdenum cofactor sulferase gene that is responsible for xanthinuria type II. Metabolism. 2003 Nov; 52(11): 1501-4.